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Taizhou Crene Biotechnology Co., Ltd.

Taizhou Crene Biotechnology Co., Ltd.is specialized in the manufacture of APIs, pharmaceutical intermediates. Our company is located in the largest API base in China--Taizhou and Cooperated to established GMP standard production base and laboratory in surrounding areas.

Our factory is a high-tech manufactory, which is committed to producing high quality pharmaceutical intermediates, promoting innovation in API technology and provide customized services for global pharmaceutical companies, dedicates itself on research, develop and industrialize of high-end intermediates & API.   We have three R&D centers from Ji’nan, Tianjin and Nanjing, more than 40 R&D staff including 5 doctors, 20 masters and 18 synthesis assistants, along with their unique advantages in the product development, pilot and process optimization, of total hundred employees. Our products are highly praised by global customers as we are Closed cooperation with domestic pharmaceutical companies, with International market of India by intermediates, South American by APIs and actively develop the European and American market, cooperated with customers to DMF registration. We bought the land with 40 mu (around 30000 square meter) in Ningyang Fine Chemical Industry Park, Tai’an., which is a provincial chemical industry park, established a high standard new manufactory, is about to set up cGMP quality system. Our new plant including 500㎡ analysis laboratories equipped with HPLC, LC-MS, GC and other analytical facilities, one pilot and four mass production workshop, the total reaction capacity can reach 35000L which can meet commercial production demands from kilos to hundreds of tons, is perfect for analysis and production.

Our mail products: Bimatoprost; Latanoprost; Travoprost; Tafluprost; Lubiprostone; Cloprostenol sodium; (+)-Cloprostenol isopropyl ester; Bimatoprost isopropyl este; Iloprost; Latanoprostene bunod ; (-)-Corey lactone diol; (±)-Corey lactone diol ect.

Our belief is "Mutual Benefits, High Efficiency". Our company has made great progress these    years. We aim at market analysis, technical innovation and constantly get the supports from the universities,and scientific research institution. So we can constantly improve the quality and upgrade our products. Now, the organization is prefect in the company, we possess a complete set of equipment for testing production. Our products sell well both in domestic and foreign market.

Contact Information

Address

  • Address:Economic Developed Zone of Taizhou Zhejiang China.
  • Taizhou
  • Zhejiang
  • 318000

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afatinib dimaleate

afatinib dimaleate

  • CAS Number: 850140-73-7
  • Quantity: 1g
  • Purity: 99% min
Afatinib dimaleate is an irreversible, dual EGFR/HER2 inhibitor, shows potent activity against wild-type and mutant forms of EGFR and HER2, with IC50 of 0.5 nM, 0.4 nM, 10 nM and…
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Cloprostenol

Cloprostenol

  • CAS Number: 40665-92-7
  • Quantity: 1g
  • Purity: 98% min
Cloprostenol is a synthetic prostaglandin analogue.
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Carboprost

Carboprost

  • CAS Number: 35700-23-3
  • Quantity: 1g
  • Purity: 98% min
Carboprost is a synthetic prostaglandin analogue of PGF2α with oxytocic properties. Properties: Appearance & Physical State: White or almost white powder Density: 1.153g/cm3 Boiling Point: 531ºC at 760 mmHg Melting…
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Dinoprost Prostaglandin F2a

Dinoprost Prostaglandin F2a

  • CAS Number: 551-11-1
  • Quantity: 1g
  • Purity: 98% min
Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost (INN), is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. In domestic mammals, it is…
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Treprostinil sodium

Treprostinil sodium

  • CAS Number: 289480-64-4
  • Quantity: 1g
  • Purity: 99% min
Treprostinil has high affinity for the DP1, EP2 and IP receptors (Ki=4.4, 3.6 and 32 nM, respectively), low affinity for EP1 and EP4 receptors and even lower affinity for EP3,…
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Isopropyl unoprostone

Isopropyl unoprostone

  • CAS Number: 120373-24-2
  • Quantity: 1g
  • Purity: 99% min
Unoprostone isopropyl is a prostanoid and synthetic docosanoid approved for the treatment of open-angle glaucoma and ocular hypertension.
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N-Cyclopropyl Bimatoprost

N-Cyclopropyl Bimatoprost

  • CAS Number: 1138395-12-6
  • Quantity: 1g
  • Purity: 99% min
N-Cyclopropyl Bimatoprost Synonyms:(5Z)-N-Cyclopropyl-7-[(2R)-3,5-dihydroxy-2-(3-hydroxy-5-phenyl-1- penten-1-yl)cyclopentyl]-5-heptenamide
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dehydrate limaprost

dehydrate limaprost

  • CAS Number: 853998-94-4
  • Quantity: 1g
  • Purity: 99% min
dehydrate limaprost 10,11-Dehydroxy Limaprost is an impurity of Limaprost.
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15S-(±)-Cloprostenol

15S-(±)-Cloprostenol

  • CAS Number: 40665-93-8
  • Quantity: 1g
  • Purity: 99% min
15S-(±)-Cloprostenol Properties: Density: 1.321g/cm3 Boiling Point: 628ºC at 760 mmHg Flash Point: 333.6ºC Refractive Index: 1.622
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5,6-trans Travoprost

5,6-trans Travoprost

  • CAS Number: 1563176-59-9
  • Quantity: 1g
  • Purity: 99% min
5,6-trans Travoprost Synonyms: 5,6-trans Travoprost;(5E)-7-[(1R,3R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoroMethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester;(5E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid 1-methylethyl ester;MKPLKVHSHYCHOC-JPVYXPJZSA-N
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15S-Travoprost

15S-Travoprost

  • CAS Number: 340181-93-3
  • Quantity: 1g
  • Purity: 99% min
15S-Travoprost Synonyms: 5-Heptenoic acid, 7-[(1S,2S,3S,5R)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-4-[3-(trifluoroMethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, 1-Methylethyl ester, (5Z)-;(5Z)-7-[(1S,2S,3S,5R)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic acid 1-methylethyl ester;15S-Travoprost;15S-Travopros;isopropyl (Z)-7-((1S,2S,3S,5R)-3,5-dihydroxy-2-((S,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoate
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(15R)-Bimatoprost

(15R)-Bimatoprost

  • CAS Number: 1163135-92-9
  • Quantity: 1g
  • Purity: 99% min
(15R)-Bimatoprost An intermediate in the production of Bimatoprost.
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Bimatoprost

Bimatoprost

  • CAS Number: 155206-00-1
  • Quantity: 1g
  • Purity: 99% min
Bimatoprost mildly stimulates the rate of aqueous humor flow during the day (13%) and at night (14%), its ocular hypotensive action is due primarily to a 26% reduction in the…
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Bimatoprost isopropyl ester

Bimatoprost isopropyl ester

  • CAS Number: 130209-76-6
  • Quantity: 1g
  • Purity: 99% min
Bimatoprost isopropyl ester is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost.1 The N-ethyl amide prostaglandin…
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Latanoprost

Latanoprost

  • CAS Number: 130209-82-4
  • Quantity: 1g
  • Purity: 98% min
Latanoprost functioned as both an indirect activator of AMP-activated protein kinase and a selective retinoid X receptor α (RXRα) antagonist able to selectively antagonise the transcription of a RXRα/peroxisome proliferator-activated…
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Latanoprostene bunod

Latanoprostene bunod

  • CAS Number: 860005-21-6
  • Quantity: 1g
  • Purity: 99% min
Latanoprostene bunod is a a nitric oxide (NO)-donating latanoprost with prostaglandin activity. It loweres intraocular pressure (IOP) more effectively than latanoprost in monkeys, dogs and rabbits.
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Lubiprostone

Lubiprostone

  • CAS Number: 136790-76-6
  • Quantity: 1g
  • Purity: 99% min
Lubiprostone induces a robust secretory response in T84 monolayers. Lubiprostone induces a rise in cAMP levels that was sensitive to EP(4)-receptor blockage in T84 cells. [1] Lubiprostone induces a contraction…
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Travoprost

Travoprost

  • CAS Number: 157283-68-6
  • Quantity: 1g
  • Purity: 98% min
Travoprost is a PGF2a analog that was launched as an ophthalmic solution administered topically for the treatment of elevated intraocular hypertension as a result of open-angle glaucoma, a common optic…
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Tafluprost

Tafluprost

  • CAS Number: 209860-87-7
  • Quantity: 1g
  • Purity: 99% min
Tafluprost(AFP-168) is an anti-glaucoma prostaglandin (PG) analog. Target:Others Tafluprost showed significant IOP-lowering effects without any safety concerns in patients with various types of glaucoma and OH in daily clinical practice…
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Dinoprostone

Dinoprostone

  • CAS Number: 363-24-6
  • Quantity: 1g
  • Purity: 99% min
Dinoprostone has important effects in labour (softening the cervix and causing uterine contraction) and also stimulates osteoblasts to release factors that stimulate bone resorption by osteoclasts.
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Dinoprost tromethamine

Dinoprost tromethamine

  • CAS Number: 38562-01-5
  • Quantity: 1g
  • Purity: 99% min
Dinoprost tromethamine(Prostaglandin F2α) tromethamine salt is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
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Prostaglandin E1 (Alprostadil)

Prostaglandin E1 (Alprostadil)

  • CAS Number: 745-65-3
  • Quantity: 1g
  • Purity: 99%min
Prostaglandin E1 (Alprostadil)is a prostaglandin, which is used in the treatment of erectile dysfunction and has vasodilatory properties. Target: Prostaglandin Receptor Prostaglandin E1 (PGE1), known pharmaceutically as alprostadil, is a…
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Iloprost

Iloprost

  • CAS Number: 78919-13-8
  • Quantity: 1g
  • Purity: 99% min
Iloprost (ZK 36374) is a synthetic analogue of prostacyclin PGI2. Target: Iloprost is a stable prostacyclin analog commonly employed in the treatment of peripheral vascular disease and also indicated in…
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Limaprost

Limaprost

  • CAS Number: 74397-12-9
  • Quantity: 1g
  • Purity: 99%
Limaprost(OP1206) is a PGE1 analog and potent platelet adhesion inhibitor. Target: Others Limaprost, an alprostadil (prostaglandin E1) analogue, is a vasodilator that increases blood flow and inhibits platelet aggregation. Limaprost…
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Carboprost Tromethamine

Carboprost Tromethamine

  • CAS Number: 58551-69-2
  • Quantity: 1g
  • Purity: 99%
Limaprost(OP1206) is a PGE1 analog and potent platelet adhesion inhibitor. Target: Others Limaprost, an alprostadil (prostaglandin E1) analogue, is a vasodilator that increases blood flow and inhibits platelet aggregation. Limaprost…
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D-Cloprostenol isopropyl ester

D-Cloprostenol isopropyl ester

  • CAS Number: 157283-66-4
  • Quantity: 1g
  • Purity: 99%
D-Cloprostenol isopropyl ester is an isopropyl ester derivative of Cloprostenol (C587300); an aryl-oxymethyl analog of prostaglandin F2α.
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(+/-)-Corey lactone diol

(+/-)-Corey lactone diol

  • CAS Number: 54423-47-1
  • Quantity: 1g
  • Purity: 99%
(±)-Corey lactone diol Synonyms: Lubiprostone Related Compound 6 (3aR,4S,5R,6aS)-hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one; (+/-)-Corey lactone diol; (+/-)-CIS-7-HYDROXY-6-HYDROXYMETHYL-2-OXABICYCLO[3.3.0]OCTAN-3-ONE; 5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one;
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(-)-Corey lactone diol

(-)-Corey lactone diol

  • CAS Number: 32233-40-2
  • Quantity: 1g
  • Purity: 99%
(-)-Corey Lactone Diol is an intermediate of Iloprost and shows inhibitory activity towards Beta-lactamase. Iloprost is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma,…
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D-Cloprostenol sodium

D-Cloprostenol sodium

  • CAS Number: 62561-03-9
  • Quantity: 1g
  • Purity: 99%
D-Cloprostenol sodium(15 g per head) is the lowest dose that consistently achieves abortion; D-cloprostenol causes mild adverse effects including salivation, defecation and hyperventilation in bitches weighing less than 10 kg.…
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selamectin

selamectin

  • CAS Number: 220119-17-5
  • Quantity: 1g
  • Purity: 99%
selamectin is a topical parasiticide and anthelminthic used on dogs and cats. It treats and prevents infections of heartworms, fleas, ear mites, sarcoptic mange (scabies), and certain types of ticks…
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Doramectin

Doramectin

  • CAS Number: 117704-25-3
  • Quantity: 1g
  • Purity: 99%
Doramectin is an antiparasitic agent.IC50 Value:Target: AntiparasiticDoramectin (Dectomax) is a veterinary drug approved by the Food and Drug Administration (FDA) for the treatment of parasites such as gastrointestinal roundworms, lungworms,…
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Moxidectin

Moxidectin

  • CAS Number: 113507-06-5
  • Quantity: 1g
  • Purity: 99%
Moxidectin is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms. Moxidectin is a semisynthetic derivative of nemadectin…
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Milbemycin oxime

Milbemycin oxime

  • CAS Number: 129496-10-2
  • Quantity: 1g
  • Purity: 99%
Milbemycin oxime is a veterinary drug from the group of milbemycins, used as a broad spectrum antiparasitic. It is active against worms (anthelmintic), insects (insecticide) and mites (miticide). Milbemycin oxime…
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trilostane Win 24540

trilostane Win 24540

  • CAS Number: 13647-35-3
  • Quantity: 1g
  • Purity: 99%
trilostane Win 24540 is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. It was withdrawn from the United States market in April 1994. However, it was…
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UD-CG115 Pimobendan

UD-CG115 Pimobendan

  • CAS Number: 74150-27-9
  • Quantity: 1g
  • Purity: 99%
UD-CG115 Pimobendan is a veterinary medication. Pimobendan is both a calcium sensitizer and a selective inhibitor of phosphodiesterase III (PDE3) with positive inotropic and vasodilator effects. Pimobendan is used in…
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Maropitant citrate hydrate

Maropitant citrate hydrate

  • CAS Number: 359875-09-5
  • Quantity: 1g
  • Purity: 99%
Maropitant citrate is a neurokinin receptor antagonist with antiemetic activity. Properties: Appearance & Physical State: UN 3284 6.1/PG 3 Melting Point: 153-159ºC(lit.) Boiling Point: 572.6ºC at 760 mmHg Flash Point:…
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Tiamulin fumarate

Tiamulin fumarate

  • CAS Number: 55297-96-6
  • Quantity: 1g
  • Purity: 99%
Tiamulin is a diterpenic veterinary drug widely used in swine for the control of infectious diseases, including swine dysentery and enzootic pneumonia. Tiamulin fumarate is a semisynthetic pleuromutilin antibiotic that…
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Cetuximab

Cetuximab

  • CAS Number: 205923-56-4
  • Quantity: 1g
  • Purity: 99%
Cetuximab is an epidermal growth factor receptor (EGFR) inhibitor used for the treatment of metastatic colorectal cancer, metastatic non-small cell lung cancer and head and neck cancer. Cetuximab is a…
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Anidulafungin (LY303366)

Anidulafungin (LY303366)

  • CAS Number: 166663-25-8
  • Quantity: 1g
  • Purity: 99%
Anidulafungin (LY303366) is a new semisynthetic echinocandin with antifungal potency. Anidulafungin (LY-303366) has MICs of ≤0.32 μg/mL for all Candida albicans (n=99), Candida glabrata (n=18), and Candida tropicalis (n=10) isolates…
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Echinocandin B

Echinocandin B

  • CAS Number: 79411-15-7
  • Quantity: 1g
  • Purity: 99%
Echinocandin B Properties: Density: 1.6 Boiling Point: 1330.8ºC at 760 mmHg Flash Point: 758.6ºC Refractive Index: 1.689
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ECBN HCL

ECBN HCL

  • CAS Number: 1029890-89-8
  • Quantity: 1g
  • Purity: 99%
ECBN HCL Synonyms: 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1);Echinocandin B nucleus hydrochloride;ECBN;ECBN HCL;1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride;1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1;Anidulafungin Nucleus Smiles O=C1N2[C@@](C(N[C@@H]([C@@H](C[C@@H](C(NC([C@H](O)C)C(N3[C@](C[C@@H](O)C3)([H])C(NC([C@H](O)[C@H](C4=CC=C(O)C=C4)O)C(N[C@@]1([H])[C@H](O)C)=O)=O)=O)=O)N)O)O)=O)([H])[C@@H](O)[C@@H](C)C2.Cl InChI InChI=1S/C34H51N7O15.ClH/c1-12-10-41-24(25(12)47)32(54)39-30(52)20(46)9-18(35)28(50)36-21(13(2)42)33(55)40-11-17(45)8-19(40)29(51)38-23(31(53)37-22(14(3)43)34(41)56)27(49)26(48)15-4-6-16(44)7-5-15;/h4-7,12-14,17-27,30,42-49,52H,8-11,35H2,1-3H3,(H,36,50)(H,37,53)(H,38,51)(H,39,54);1H/t12-,13+,14+,17+,18-,19-,20+,21?,22-,23?,24-,25-,26-,27-,30+;/m0./s1
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Micafungin sodium

Micafungin sodium

  • CAS Number: 208538-73-2
  • Quantity: 1g
  • Purity: 98%
Micafungin sodium is an inhibitor of 1, 3-beta-D-glucan synthesis, and used as an antifungal drug. Micafungin (10 mg/mL) phenotypicly decreases the formation of biofilm in most of the isolates. For…
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Micafungin FR-179642 impurity acid

Micafungin FR-179642 impurity acid

  • CAS Number: 168110-44-9
  • Quantity: 1g
  • Purity: 99%
FR 179642 is an impurity of Micafungin, a lipopeptide compound that acts as an antifungal agent with activity against Aspergillus and Candida species.
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Caspofungin acetate

Caspofungin acetate

  • CAS Number: 179463-17-3
  • Quantity: 1g
  • Purity: 99%
Caspofungin acetate is an lipopeptide antifungal β-1,3-glucan synthase inhibitor. Mice injected with caspofungin at vitreal concentrations from 0.41 to 4.1 μM do not have significant alterations in their ERG waveforms,…
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Pneumocandin B0

Pneumocandin B0

  • CAS Number: 135575-42-7
  • Quantity: 1g
  • Purity: 99%
Pneumocandin B0(L-688786), a key intermediate in the synthesis of the antifungal agent, Cancidas, has led to the identification of several materials with potential for improved performance.