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Taizhou Crene Biotechnology Co., Ltd.

Taizhou Crene Biotechnology Co., Ltd.is specialized in the manufacture of APIs, pharmaceutical intermediates. Our company is located in the largest API base in China--Taizhou and Cooperated to established GMP standard production base and laboratory in surrounding areas.

Our factory is a high-tech manufactory, which is committed to producing high quality pharmaceutical intermediates, promoting innovation in API technology and provide customized services for global pharmaceutical companies, dedicates itself on research, develop and industrialize of high-end intermediates & API.   We have three R&D centers from Ji’nan, Tianjin and Nanjing, more than 40 R&D staff including 5 doctors, 20 masters and 18 synthesis assistants, along with their unique advantages in the product development, pilot and process optimization, of total hundred employees. Our products are highly praised by global customers as we are Closed cooperation with domestic pharmaceutical companies, with International market of India by intermediates, South American by APIs and actively develop the European and American market, cooperated with customers to DMF registration. We bought the land with 40 mu (around 30000 square meter) in Ningyang Fine Chemical Industry Park, Tai’an., which is a provincial chemical industry park, established a high standard new manufactory, is about to set up cGMP quality system. Our new plant including 500㎡ analysis laboratories equipped with HPLC, LC-MS, GC and other analytical facilities, one pilot and four mass production workshop, the total reaction capacity can reach 35000L which can meet commercial production demands from kilos to hundreds of tons, is perfect for analysis and production.

Our mail products: Bimatoprost; Latanoprost; Travoprost; Tafluprost; Lubiprostone; Cloprostenol sodium; (+)-Cloprostenol isopropyl ester; Bimatoprost isopropyl este; Iloprost; Latanoprostene bunod ; (-)-Corey lactone diol; (±)-Corey lactone diol ect.

Our belief is "Mutual Benefits, High Efficiency". Our company has made great progress these    years. We aim at market analysis, technical innovation and constantly get the supports from the universities,and scientific research institution. So we can constantly improve the quality and upgrade our products. Now, the organization is prefect in the company, we possess a complete set of equipment for testing production. Our products sell well both in domestic and foreign market.

Contact Information

Address

  • Address:Economic Developed Zone of Taizhou Zhejiang China.
  • Taizhou
  • Zhejiang
  • 318000

Contact Form:

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afatinib dimaleate

afatinib dimaleate

  • CAS Number: 850140-73-7
  • Quantity: 1g
  • Purity: 99% min
Afatinib dimaleate is an irreversible, dual EGFR/HER2 inhibitor, shows potent activity against wild-type and mutant forms of EGFR and HER2, with IC50 of 0.5 nM, 0.4 nM, 10 nM and…
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Cloprostenol

Cloprostenol

  • CAS Number: 40665-92-7
  • Quantity: 1g
  • Purity: 98% min
Cloprostenol is a synthetic prostaglandin analogue.
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Carboprost

Carboprost

  • CAS Number: 35700-23-3
  • Quantity: 1g
  • Purity: 98% min
Carboprost is a synthetic prostaglandin analogue of PGF2α with oxytocic properties. Properties: Appearance & Physical State: White or almost white powder Density: 1.153g/cm3 Boiling Point: 531ºC at 760 mmHg Melting…
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Dinoprost Prostaglandin F2a

Dinoprost Prostaglandin F2a

  • CAS Number: 551-11-1
  • Quantity: 1g
  • Purity: 98% min
Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost (INN), is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. In domestic mammals, it is…
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Treprostinil sodium

Treprostinil sodium

  • CAS Number: 289480-64-4
  • Quantity: 1g
  • Purity: 99% min
Treprostinil has high affinity for the DP1, EP2 and IP receptors (Ki=4.4, 3.6 and 32 nM, respectively), low affinity for EP1 and EP4 receptors and even lower affinity for EP3,…
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Isopropyl unoprostone

Isopropyl unoprostone

  • CAS Number: 120373-24-2
  • Quantity: 1g
  • Purity: 99% min
Unoprostone isopropyl is a prostanoid and synthetic docosanoid approved for the treatment of open-angle glaucoma and ocular hypertension.
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N-Cyclopropyl Bimatoprost

N-Cyclopropyl Bimatoprost

  • CAS Number: 1138395-12-6
  • Quantity: 1g
  • Purity: 99% min
N-Cyclopropyl Bimatoprost Synonyms:(5Z)-N-Cyclopropyl-7-[(2R)-3,5-dihydroxy-2-(3-hydroxy-5-phenyl-1- penten-1-yl)cyclopentyl]-5-heptenamide
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dehydrate limaprost

dehydrate limaprost

  • CAS Number: 853998-94-4
  • Quantity: 1g
  • Purity: 99% min
dehydrate limaprost 10,11-Dehydroxy Limaprost is an impurity of Limaprost.
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15S-(±)-Cloprostenol

15S-(±)-Cloprostenol

  • CAS Number: 40665-93-8
  • Quantity: 1g
  • Purity: 99% min
15S-(±)-Cloprostenol Properties: Density: 1.321g/cm3 Boiling Point: 628ºC at 760 mmHg Flash Point: 333.6ºC Refractive Index: 1.622
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5,6-trans Travoprost

5,6-trans Travoprost

  • CAS Number: 1563176-59-9
  • Quantity: 1g
  • Purity: 99% min
5,6-trans Travoprost Synonyms: 5,6-trans Travoprost;(5E)-7-[(1R,3R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoroMethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester;(5E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid 1-methylethyl ester;MKPLKVHSHYCHOC-JPVYXPJZSA-N
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15S-Travoprost

15S-Travoprost

  • CAS Number: 340181-93-3
  • Quantity: 1g
  • Purity: 99% min
15S-Travoprost Synonyms: 5-Heptenoic acid, 7-[(1S,2S,3S,5R)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-4-[3-(trifluoroMethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, 1-Methylethyl ester, (5Z)-;(5Z)-7-[(1S,2S,3S,5R)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic acid 1-methylethyl ester;15S-Travoprost;15S-Travopros;isopropyl (Z)-7-((1S,2S,3S,5R)-3,5-dihydroxy-2-((S,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoate
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(15R)-Bimatoprost

(15R)-Bimatoprost

  • CAS Number: 1163135-92-9
  • Quantity: 1g
  • Purity: 99% min
(15R)-Bimatoprost An intermediate in the production of Bimatoprost.
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Bimatoprost

Bimatoprost

  • CAS Number: 155206-00-1
  • Quantity: 1g
  • Purity: 99% min
Bimatoprost mildly stimulates the rate of aqueous humor flow during the day (13%) and at night (14%), its ocular hypotensive action is due primarily to a 26% reduction in the…
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Bimatoprost isopropyl ester

Bimatoprost isopropyl ester

  • CAS Number: 130209-76-6
  • Quantity: 1g
  • Purity: 99% min
Bimatoprost isopropyl ester is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost.1 The N-ethyl amide prostaglandin…
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Latanoprost

Latanoprost

  • CAS Number: 130209-82-4
  • Quantity: 1g
  • Purity: 98% min
Latanoprost functioned as both an indirect activator of AMP-activated protein kinase and a selective retinoid X receptor α (RXRα) antagonist able to selectively antagonise the transcription of a RXRα/peroxisome proliferator-activated…
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Latanoprostene bunod

Latanoprostene bunod

  • CAS Number: 860005-21-6
  • Quantity: 1g
  • Purity: 99% min
Latanoprostene bunod is a a nitric oxide (NO)-donating latanoprost with prostaglandin activity. It loweres intraocular pressure (IOP) more effectively than latanoprost in monkeys, dogs and rabbits.
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Lubiprostone

Lubiprostone

  • CAS Number: 136790-76-6
  • Quantity: 1g
  • Purity: 99% min
Lubiprostone induces a robust secretory response in T84 monolayers. Lubiprostone induces a rise in cAMP levels that was sensitive to EP(4)-receptor blockage in T84 cells. [1] Lubiprostone induces a contraction…
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Travoprost

Travoprost

  • CAS Number: 157283-68-6
  • Quantity: 1g
  • Purity: 98% min
Travoprost is a PGF2a analog that was launched as an ophthalmic solution administered topically for the treatment of elevated intraocular hypertension as a result of open-angle glaucoma, a common optic…
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Tafluprost

Tafluprost

  • CAS Number: 209860-87-7
  • Quantity: 1g
  • Purity: 99% min
Tafluprost(AFP-168) is an anti-glaucoma prostaglandin (PG) analog. Target:Others Tafluprost showed significant IOP-lowering effects without any safety concerns in patients with various types of glaucoma and OH in daily clinical practice…
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Dinoprostone

Dinoprostone

  • CAS Number: 363-24-6
  • Quantity: 1g
  • Purity: 99% min
Dinoprostone has important effects in labour (softening the cervix and causing uterine contraction) and also stimulates osteoblasts to release factors that stimulate bone resorption by osteoclasts.
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Dinoprost tromethamine

Dinoprost tromethamine

  • CAS Number: 38562-01-5
  • Quantity: 1g
  • Purity: 99% min
Dinoprost tromethamine(Prostaglandin F2α) tromethamine salt is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
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Prostaglandin E1 (Alprostadil)

Prostaglandin E1 (Alprostadil)

  • CAS Number: 745-65-3
  • Quantity: 1g
  • Purity: 99%min
Prostaglandin E1 (Alprostadil)is a prostaglandin, which is used in the treatment of erectile dysfunction and has vasodilatory properties. Target: Prostaglandin Receptor Prostaglandin E1 (PGE1), known pharmaceutically as alprostadil, is a…
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Iloprost

Iloprost

  • CAS Number: 78919-13-8
  • Quantity: 1g
  • Purity: 99% min
Iloprost (ZK 36374) is a synthetic analogue of prostacyclin PGI2. Target: Iloprost is a stable prostacyclin analog commonly employed in the treatment of peripheral vascular disease and also indicated in…
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Limaprost

Limaprost

  • CAS Number: 74397-12-9
  • Quantity: 1g
  • Purity: 99%
Limaprost(OP1206) is a PGE1 analog and potent platelet adhesion inhibitor. Target: Others Limaprost, an alprostadil (prostaglandin E1) analogue, is a vasodilator that increases blood flow and inhibits platelet aggregation. Limaprost…
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Carboprost Tromethamine

Carboprost Tromethamine

  • CAS Number: 58551-69-2
  • Quantity: 1g
  • Purity: 99%
Limaprost(OP1206) is a PGE1 analog and potent platelet adhesion inhibitor. Target: Others Limaprost, an alprostadil (prostaglandin E1) analogue, is a vasodilator that increases blood flow and inhibits platelet aggregation. Limaprost…
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D-Cloprostenol isopropyl ester

D-Cloprostenol isopropyl ester

  • CAS Number: 157283-66-4
  • Quantity: 1g
  • Purity: 99%
D-Cloprostenol isopropyl ester is an isopropyl ester derivative of Cloprostenol (C587300); an aryl-oxymethyl analog of prostaglandin F2α.
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(+/-)-Corey lactone diol

(+/-)-Corey lactone diol

  • CAS Number: 54423-47-1
  • Quantity: 1g
  • Purity: 99%
(±)-Corey lactone diol Synonyms: Lubiprostone Related Compound 6 (3aR,4S,5R,6aS)-hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one; (+/-)-Corey lactone diol; (+/-)-CIS-7-HYDROXY-6-HYDROXYMETHYL-2-OXABICYCLO[3.3.0]OCTAN-3-ONE; 5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one;
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(-)-Corey lactone diol

(-)-Corey lactone diol

  • CAS Number: 32233-40-2
  • Quantity: 1g
  • Purity: 99%
(-)-Corey Lactone Diol is an intermediate of Iloprost and shows inhibitory activity towards Beta-lactamase. Iloprost is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma,…
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D-Cloprostenol sodium

D-Cloprostenol sodium

  • CAS Number: 62561-03-9
  • Quantity: 1g
  • Purity: 99%
D-Cloprostenol sodium(15 g per head) is the lowest dose that consistently achieves abortion; D-cloprostenol causes mild adverse effects including salivation, defecation and hyperventilation in bitches weighing less than 10 kg.…
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selamectin

selamectin

  • CAS Number: 220119-17-5
  • Quantity: 1g
  • Purity: 99%
selamectin is a topical parasiticide and anthelminthic used on dogs and cats. It treats and prevents infections of heartworms, fleas, ear mites, sarcoptic mange (scabies), and certain types of ticks…
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Doramectin

Doramectin

  • CAS Number: 117704-25-3
  • Quantity: 1g
  • Purity: 99%
Doramectin is an antiparasitic agent.IC50 Value:Target: AntiparasiticDoramectin (Dectomax) is a veterinary drug approved by the Food and Drug Administration (FDA) for the treatment of parasites such as gastrointestinal roundworms, lungworms,…
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Moxidectin

Moxidectin

  • CAS Number: 113507-06-5
  • Quantity: 1g
  • Purity: 99%
Moxidectin is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms. Moxidectin is a semisynthetic derivative of nemadectin…
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Milbemycin oxime

Milbemycin oxime

  • CAS Number: 129496-10-2
  • Quantity: 1g
  • Purity: 99%
Milbemycin oxime is a veterinary drug from the group of milbemycins, used as a broad spectrum antiparasitic. It is active against worms (anthelmintic), insects (insecticide) and mites (miticide). Milbemycin oxime…
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trilostane Win 24540

trilostane Win 24540

  • CAS Number: 13647-35-3
  • Quantity: 1g
  • Purity: 99%
trilostane Win 24540 is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. It was withdrawn from the United States market in April 1994. However, it was…
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UD-CG115 Pimobendan

UD-CG115 Pimobendan

  • CAS Number: 74150-27-9
  • Quantity: 1g
  • Purity: 99%
UD-CG115 Pimobendan is a veterinary medication. Pimobendan is both a calcium sensitizer and a selective inhibitor of phosphodiesterase III (PDE3) with positive inotropic and vasodilator effects. Pimobendan is used in…
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Maropitant citrate hydrate

Maropitant citrate hydrate

  • CAS Number: 359875-09-5
  • Quantity: 1g
  • Purity: 99%
Maropitant citrate is a neurokinin receptor antagonist with antiemetic activity. Properties: Appearance & Physical State: UN 3284 6.1/PG 3 Melting Point: 153-159ºC(lit.) Boiling Point: 572.6ºC at 760 mmHg Flash Point:…
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Tiamulin fumarate

Tiamulin fumarate

  • CAS Number: 55297-96-6
  • Quantity: 1g
  • Purity: 99%
Tiamulin is a diterpenic veterinary drug widely used in swine for the control of infectious diseases, including swine dysentery and enzootic pneumonia. Tiamulin fumarate is a semisynthetic pleuromutilin antibiotic that…
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Cetuximab

Cetuximab

  • CAS Number: 205923-56-4
  • Quantity: 1g
  • Purity: 99%
Cetuximab is an epidermal growth factor receptor (EGFR) inhibitor used for the treatment of metastatic colorectal cancer, metastatic non-small cell lung cancer and head and neck cancer. Cetuximab is a…
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Anidulafungin (LY303366)

Anidulafungin (LY303366)

  • CAS Number: 166663-25-8
  • Quantity: 1g
  • Purity: 99%
Anidulafungin (LY303366) is a new semisynthetic echinocandin with antifungal potency. Anidulafungin (LY-303366) has MICs of ≤0.32 μg/mL for all Candida albicans (n=99), Candida glabrata (n=18), and Candida tropicalis (n=10) isolates…
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Echinocandin B

Echinocandin B

  • CAS Number: 79411-15-7
  • Quantity: 1g
  • Purity: 99%
Echinocandin B Properties: Density: 1.6 Boiling Point: 1330.8ºC at 760 mmHg Flash Point: 758.6ºC Refractive Index: 1.689
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ECBN HCL

ECBN HCL

  • CAS Number: 1029890-89-8
  • Quantity: 1g
  • Purity: 99%
ECBN HCL Synonyms: 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1);Echinocandin B nucleus hydrochloride;ECBN;ECBN HCL;1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride;1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1;Anidulafungin Nucleus Smiles O=C1N2[C@@](C(N[C@@H]([C@@H](C[C@@H](C(NC([C@H](O)C)C(N3[C@](C[C@@H](O)C3)([H])C(NC([C@H](O)[C@H](C4=CC=C(O)C=C4)O)C(N[C@@]1([H])[C@H](O)C)=O)=O)=O)=O)N)O)O)=O)([H])[C@@H](O)[C@@H](C)C2.Cl InChI InChI=1S/C34H51N7O15.ClH/c1-12-10-41-24(25(12)47)32(54)39-30(52)20(46)9-18(35)28(50)36-21(13(2)42)33(55)40-11-17(45)8-19(40)29(51)38-23(31(53)37-22(14(3)43)34(41)56)27(49)26(48)15-4-6-16(44)7-5-15;/h4-7,12-14,17-27,30,42-49,52H,8-11,35H2,1-3H3,(H,36,50)(H,37,53)(H,38,51)(H,39,54);1H/t12-,13+,14+,17+,18-,19-,20+,21?,22-,23?,24-,25-,26-,27-,30+;/m0./s1
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Micafungin sodium

Micafungin sodium

  • CAS Number: 208538-73-2
  • Quantity: 1g
  • Purity: 98%
Micafungin sodium is an inhibitor of 1, 3-beta-D-glucan synthesis, and used as an antifungal drug. Micafungin (10 mg/mL) phenotypicly decreases the formation of biofilm in most of the isolates. For…
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Micafungin FR-179642 impurity acid

Micafungin FR-179642 impurity acid

  • CAS Number: 168110-44-9
  • Quantity: 1g
  • Purity: 99%
FR 179642 is an impurity of Micafungin, a lipopeptide compound that acts as an antifungal agent with activity against Aspergillus and Candida species.
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Caspofungin acetate

Caspofungin acetate

  • CAS Number: 179463-17-3
  • Quantity: 1g
  • Purity: 99%
Caspofungin acetate is an lipopeptide antifungal β-1,3-glucan synthase inhibitor. Mice injected with caspofungin at vitreal concentrations from 0.41 to 4.1 μM do not have significant alterations in their ERG waveforms,…
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Pneumocandin B0

Pneumocandin B0

  • CAS Number: 135575-42-7
  • Quantity: 1g
  • Purity: 99%
Pneumocandin B0(L-688786), a key intermediate in the synthesis of the antifungal agent, Cancidas, has led to the identification of several materials with potential for improved performance.
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Afatinib dimaleate

Afatinib dimaleate

  • CAS Number: 850140-73-7
  • Quantity: 1g
  • Purity: 99% min
Afatinib dimaleate is an orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. EGFR/HER2 tyrosine kinase inhibitor BIBW 2992 irreversibly binds to and inhibits human epidermal growth…
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Idelalisib CAL-101

Idelalisib CAL-101

  • CAS Number: 870281-82-6
  • Price: 1
  • Quantity: 1
  • Purity: 99%
CAL-101 is a highly selective and potent p110δ inhibitor with IC50 of 2.5 nM, is 40- to 300-fold more selective for p110δ relative to other PI3K class I enzymes (p110α,…
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4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline

4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline

  • CAS Number: 162012-67-1
  • Price: 1
  • Quantity: 1
  • Purity: 99%
4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline is an intermediate in the synthesis of Afatinib, an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
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Afatinib Intermediates 314771-88-5

  • CAS Number: 314771-88-5
  • Price: 1
  • Quantity: 1
  • Purity: 99%
(S)-N-(3-chloro-4-fluorophenyl)-6-nitro-7-(tetrahydrofuran-3-yloxy)quinazolin-4-amine is a used in the synthetic preparation of 4-anilinoquinazolines with C-6 urea-linked side chains as inhibitors of epidermal growth factor receptor. It is also used in the preparation of…
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Afatinib IMpurity B

Afatinib IMpurity B

  • CAS Number: 314771-76-1
  • Price: 1
  • Quantity: 1
  • Purity: 98% min
Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl is a reactant in the synthesis of Afatinib, an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
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(S)-(+)-3-Hydroxytetrahydrofuran

(S)-(+)-3-Hydroxytetrahydrofuran

  • CAS Number: 86087-23-2
  • Price: 1
  • Quantity: 1
  • Purity: 98% min
Product Name: (S)-(+)-3-Hydroxytetrahydrofuran (CAS NO.86087-23-2) Molecular Formula: C4H8O2 Molecular Weight: 88.11g/mol Appearance: Colourless Liquid Boiling point: 181 °C at 760 mmHg Flash Point: 81.1 °C Density: 1.148 g/cm3 Refractive index:…
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trans-4-Dimethylaminocrotonic acid hydrochloride

trans-4-Dimethylaminocrotonic acid hydrochloride

  • CAS Number: 848133-35-7
  • Price: 1
  • Quantity: 1
  • Purity: 98% min
Name:trans-4-dimethylaminocrotonic acid hydrochloride Cas:848133-35-7 Color:white powder Purity:99.0%min Molecular formula:C6H11NO2.HCl Molecular weight:165.62
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DIETHYLPHOSPHONOACETIC ACID

DIETHYLPHOSPHONOACETIC ACID

  • CAS Number: 3095-95-2
  • Price: 1
  • Quantity: 1
  • Purity: 98% min
Diethylphosphonoacetic Acid is a reagent that is used for enantioselective preparation of α-phosphoryl-α,β-unsatd.-δ-aryl-δ-lactones from nonracemic β-hydroxyaldehydes and their conversion to α-methylene-δ-aryl-δ-lactones. Properties: Appearance & Physical State: clear colorless to yellow…
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2,2-Diethoxy-N,N-dimethylethylamine

2,2-Diethoxy-N,N-dimethylethylamine

  • CAS Number: 3616-56-6
  • Price: 1
  • Quantity: 1
  • Purity: 98% min
Chemical Name: 2,2-Diethoxy-N,N-dimethylethylamine Properties: Appearance & Physical State: Colourless liquid Density: 0.883 Boiling Point: 170ºC Flash Point: 113 °F Refractive Index: 1.411
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Idelalisib CAL-101

Idelalisib CAL-101

  • CAS Number: 870281-82-6
  • Quantity: 1
  • Purity: 98% min
CAL-101 is a highly selective and potent p110δ inhibitor with IC50 of 2.5 nM, is 40- to 300-fold more selective for p110δ relative to other PI3K class I enzymes (p110α,…
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idelalisib intermediate

idelalisib intermediate

  • CAS Number: 870281-85-9
  • Quantity: 1
  • Purity: 98% min
CAL-101 is a highly selective and potent p110δ inhibitor with IC50 of 2.5 nM, is 40- to 300-fold more selective for p110δ relative to other PI3K class I enzymes (p110α,…
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2-(1-aMinoethyl)-6-Methyl

2-(1-aMinoethyl)-6-Methyl

  • CAS Number: 870281-86-0
  • Quantity: 1
  • Purity: 98% min
Synonyms: 2-(1-aMinoethyl)-6-Methyl; (S)-2-(1-aminoethyl)-6-methylphenol; Phenol,2-(1-aminoethyl)-6-methyl-,(S)-(9CI); (S)-2-(1-amino-propyl)-5-fluoro-3-phenyl-3H-quinazolin-4-one;
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2-Fluoro-6-nitro-N-phenylbenzamide

2-Fluoro-6-nitro-N-phenylbenzamide

  • CAS Number: 870281-83-7
  • Quantity: 1g
  • Purity: 98% min
Solubility: Insuluble (5.7E-3 g/L) (25 ºC) Density: 1.411±0.06 g/cm3 (20 ºC 760 Torr) Melting point: 163-165 ºC
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BIBF1120 Nintedanib

BIBF1120 Nintedanib

  • CAS Number: 928326-83-4
  • Quantity: 98% min
  • Purity: 99% min
Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.
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nintedanib ethanesulfonate salt

nintedanib ethanesulfonate salt

  • CAS Number: 656247-18-6
  • Quantity: 1
  • Purity: 98% min
Synonyms: Nintedanib ethanesulfonate BIBF 1120 esylate BIBF-1120 esylat Nintedanib esylat Nintedanib ethanesulfonate salt BIBF1120/nintedanib ethanesulfonate salt Trinidad Neeb esylate
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Nintedanib esylate

Nintedanib esylate

  • CAS Number: 14192-26-8
  • Quantity: 1
  • Purity: 98% min
Synonyms: Methyl 2-oxoindoline-6-carboxylate; Methyl oxindole-6-carboxylate; methyl 2-oxo-1,3-dihydroindole-6-carboxylate Mhyl 2-oxindole-6-carbo... 1-Methoxy-1H-indole-6-carboxylate Methyl 2-oxoindole-6-carboxylate 6-Methoxycarbonyl-2-oxindole methyl 2-oxo-2,3-dihydro-1H-indole-6-carboxylate Methyl2-oxoindoline-6-carboxylate97% 1H-Indole-6-carboxylicacid, 2,3-dihydro-2-oxo-, methyl ester Menthyl 2-oxoindole-6-carboxylate 2-OXO-6-INDOLINECARBOXYLIC ACID METHYL ESTER
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Nintedanib Intermediate 2

Nintedanib Intermediate 2

  • CAS Number: 262368-30-9
  • Quantity: 1
  • Purity: 98% min
Synonyms: N-[(4-methyl-piperazin-1-yl)-methylcarbonyl]-N-methyl-p-phenyldiamine; N-[(4-methyl-piperazin-1-yl)-methylcarbonyl]-N-methyl-p-phenylendiamine; N-(4-Aminophenyl)-N,4-dimethyl-1-piperazineacetamide; N-[(4-methyl-piperazin-1-yl)-methylcarbonyl]-N-methyl-p-phenylenediamine;
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N-Methyl-4-nitroaniline

N-Methyl-4-nitroaniline

  • CAS Number: 100-15-2
  • Quantity: 1
  • Purity: 98% min
Appearance & Physical State: Brownish-yellow prisms with violet reflex (from ethanol) or yellow powder Density: 1.2 Melting Point: 149-154ºC Boiling Point: 290.6ºC at 760 mmHg Flash Point: 129.5ºC Refractive Index:…
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BIBF1120 Intermediate 4

BIBF1120 Intermediate 4

  • CAS Number: 1168150-46-6
  • Quantity: 1
  • Purity: 98% min
Synonyms: (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester BIBF1120 Intermediate4 Nintedanib ethanesulfonate intermediates (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl este methyl (E)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-, methyl ester, (3E)-
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Trimethyl orthobenzoate

Trimethyl orthobenzoate

  • CAS Number: 707-07-3
  • Quantity: 1
  • Purity: 98% min
Appearance & Physical State: clear colorless liquid Density: 1.061 Boiling Point: 87-88ºC (7 mmHg) Flash Point: 82ºC Refractive Index: 1.488-1.49
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Tedizolid Phosphate

Tedizolid Phosphate

  • CAS Number: 856867-55-5
  • Quantity: 1
  • Purity: 98% min
Tedizolid phosphate is a novel oxazolidinone with activity against Gram-positive pathogens.
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Tedizolid TR-700

Tedizolid TR-700

  • CAS Number: 856866-72-3
  • Quantity: 1
  • Purity: 98% min
Tedizolid, known as TR-700, is an oral and i.v administered intracellular antibacterial drug.
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Tedizolid intermediate 1220910-89-3

Tedizolid intermediate 1220910-89-3

  • CAS Number: 1220910-89-3
  • Quantity: 1g
  • Purity: 98% min
N-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]carbamic Acid Phenylmethyl Ester is an intermediate in the synthesis of Tedizolid, an known oral and intravenous antibiotic.
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5-Bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine

5-Bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine

  • CAS Number: 380380-64-3
  • Quantity: 1
  • Purity: 98% min
5-Bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine is a reagent in the synthesis and structure-activity relationship studies of highly potent novel benzoxazinyl-oxazolidinone which is an antibacterial agents. Benzoxazinyl-oxazolidinone had potent activity against Gram-positive pathogens.
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Torezolid Intermediate 3

Torezolid Intermediate 3

  • CAS Number: 444335-16-4
  • Quantity: 1
  • Purity: 98% min
Synonyms: 2-Oxazolidinone,3-(4-bromo-3-fluorophenyl)-5-(hydroxymethyl)-, (5R)- Torezolid Intermediate3 (5R)-3-(4-BROMO-3-FLUOROPHENYL)-5-HYDROXYMETHYLOXAZOLIDIN-2-ONE (5R)-3-(4-broMo-3-fluorophenyl)-5-(hydroxyMethyl)-1,3-oxazolidin-2-one (R)-3-(4-BroMo-3-fluorophenyl)-5-(hydroxyMethyl)oxazolidin-2-one
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Tedizolid intermediate H

Tedizolid intermediate H

  • CAS Number: 1056039-83-8
  • Quantity: 1
  • Purity: 98% min
Synonyms: Pyridine, 2-(2-methyl-2H-tetrazol-5-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;2-(2-Methyl-2H-tetrazol-5-yl)-5-(4;2-(2-Methyl-2H-tetrazol-5-yl)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine;Tedizolid intermediate H;2-(2-Methyl-2H-tetrazol-5-yl)pyridine-5-boronic acid pinacol;Pinacol 2-(2-methyl-2H-tetrazol-5-yl)-5-pyridineboronate;2-(2-Methyl-2H-tetrazol-5-yl)pyridine-5-boronic acid pinacol ester
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lesinurad  878672-00-5

lesinurad 878672-00-5

  • CAS Number: 878672-00-5
  • Quantity: 1
  • Purity: 98% min
Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 uM, respectively.
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1-Cyclopropyl-4-isothiocyanatonaphthalene

1-Cyclopropyl-4-isothiocyanatonaphthalene

  • CAS Number: 878671-95-5
  • Quantity: 1
  • Purity: 98% min
Synonyms: 1-CYCLOPROPYL-4-ISOTHIOCYANATO-; 1-Cyclopropyl-4-isothiocyanatonaphthalene; 1-cyclopropyl-4-isothiocyanato-naphthalene; 1-cyclopropyl-4-isothiocyanato Naphthalene; NAPHTHALENE, 1-CYCLOPROPYL-4-ISOTHIOCYANATO-;
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Lesinurad intermediates 878671-96-6

Lesinurad intermediates 878671-96-6

  • CAS Number: 878671-96-6
  • Quantity: 1
  • Purity: 98% min
Synonyms: 3H-1,2,4-Triazole-3-thione, 5-amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro 3-Amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-5-thiol 5-amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro-3H-1,2,4-Triazole-3-thione 3-Amino-4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione 3H-1,2,4-Triazole-3-thione, 5-amino-4-(4-cyclopropyl-1-phthalenyl)-2,4-dihydro 5-amino-4-(4-cyclopropylnaphthalen-1-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione
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Lesinurad Impurity 1533519-84-4

Lesinurad Impurity 1533519-84-4

  • CAS Number: 1533519-84-4
  • Quantity: 1
  • Purity: 99.0%min
Synonyms: 4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione lesinurad int.4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione 4-(4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol Sodium 2-((4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetate 4-(4-cyclopropylnaphthalen-1-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione Lesinurad Impurity 21 4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione (for Lesinurad) 4-(4-Cyclopropylnaphthalen-1-yl)-1H-1
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4-cyclopropylnaphthalen-1-aMine hydrochloride

4-cyclopropylnaphthalen-1-aMine hydrochloride

  • CAS Number: 1533519-92-4
  • Quantity: 1
  • Purity: 98% min
Synonyms: 4-cyclopropylnaphthalen-1-aMine hydrochloride 4-cyclopropylnaphthalen-1-aMine HCl 4-Cyclopropyl-1-naphthalenamine hydrochloride (1:1) 1-Naphthalenamine, 4-cyclopropyl-, hydrochloride 4-cyclopropylnaphthalene –1-amine hydrochloride Lesinurad Impurity 14 HCl 4-Cyclopropyl-1-naphthalenamine HCl 1-Naphthalenamine, 4-cyclopropyl-, hydrochloride (1:1)
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lesinurad int

lesinurad int

  • CAS Number: 1533519-85-5
  • Quantity: 1
  • Purity: 98% min
Synonyms: lesinurad int Methyl 2-[[4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetate Acetic acid, 2-[[4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-, methyl ester 2-[[4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-, methyl ester Lesinurad Impurity 9 Methyl 2-[[4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetate(for Lesinurad) 4-triazol-3-yl]thio]acetate Methyl 2-[[4-(4-cyclopropylnaphthalen-1-yl)-4H-1
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Formylhydrazine

Formylhydrazine

  • CAS Number: 624-84-0
  • Quantity: 1
  • Purity: 98% min
Hydrazinecarboxaldehyde is used in the synthesis of azaindazoles as inhibitors of bacterial DNA ligase. Also used in the synthesis of anticonvulsants as quinoline derivatives. Properties: Appearance & Physical State: white…
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2-Naphthylamine

2-Naphthylamine

  • CAS Number: 91-59-8
  • Quantity: 1
  • Purity: 98% min
2-Naphthylamine is one of two isomeric aminonaphthalenes, compounds with the formula C10H7NH2. It is a colorless solid, but samples take on a reddish color in air because of oxidiation. The…
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carboxamide

carboxamide

  • CAS Number: 417716-92-8
  • Quantity: 1
  • Purity: 98% min
Lenvatinib is an orally active, multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, and less potent against VEGFR1/Flt-1, and approximately 10-fold more selective for VEGFR2/3 against FGFR1,…
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Lenvatinib mesylate

Lenvatinib mesylate

  • CAS Number: 857890-39-2
  • Quantity: 1
  • Purity: 98% min
Lenvatinib, also known as E7080, is a synthetic, orally available inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR/FLK-1) tyrosine kinase with potential antineoplastic activity. E7080…
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Lenvatinib Intermediates

Lenvatinib Intermediates

  • CAS Number: 417721-36-9
  • Quantity: 1
  • Purity: 98% min
Synonyms: 4-chloro-7-methoxy-quinoline-6-carboxylic acid amide; QC-5355; 6-Quinolinecarboxamide,4-chloro-7-methoxy; 7-methoxy-4-chloro-quinoline-6-carboxamide;
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Lenvatinib Intermediate 3

Lenvatinib Intermediate 3

  • CAS Number: 205448-65-3
  • Quantity: 1
  • Purity: 98% min
Synonyms: Methyl 7-Methoxy-4-oxo-1,4-dihydroquinoline-6-carboxylate 1,4-Dihydro-7-methoxy-4-oxo-6-quinolinecarboxylic acid methyl ester 7-Methoxy-4-oxo-1,4-dihydro-quinoline-6-carboxylic acid methyl ester Lenvatinib Intermediate3 FMX14227-A2 7-Methoxy-4-oxo-1,4-dihydroquinoline-6-carboxylate methyl 4-hydroxy-7-methoxyquinoline-6-carboxylate 4-dihydroquinoline-6-carboxylate
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4-Amino-3-chlorophenol

4-Amino-3-chlorophenol

  • CAS Number: 17609-80-2
  • Quantity: 1
  • Purity: 98% min
Synonyms: EINECS 241-583-3; 2-chloro-4-hydroxyaniline; 4-amino-3-chloro-phenol; 3-chloro-p-aminophenol; 3-Chloro-4-aminophenol;
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4-AMINO-3-CHLOROPHENOL HCL

4-AMINO-3-CHLOROPHENOL HCL

  • CAS Number: 52671-64-4
  • Quantity: 1
  • Purity: 98% min
Synonyms: EINECS 241-583-3; 2-chloro-4-hydroxyaniline; 4-amino-3-chloro-phenol; 3-chloro-p-aminophenol; 3-Chloro-4-aminophenol;
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Vonoprazan

Vonoprazan

  • CAS Number: 1260141-27-2
  • Quantity: 1
  • Purity: 98% min
Vonoprazan fumarate is a first-in-class potassium-competitive acid blocker. Vonoprazan can be used for the treatment of gastroduodenal ulcer (including some drug-induced peptic ulcers) and reflux esophagitis, and can be combined…
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3-Pyridine sulphonyl chloride

3-Pyridine sulphonyl chloride

  • CAS Number: 16133-25-8
  • Quantity: 1
  • Purity: 98% min
Density: 1.489 g/cm3 Melting Point: 144ºC Boiling Point: 284.162ºC at 760 mmHg Flash Point: 125.657ºC Vapor Pressure: 0.000344mmHg at 25°C Safety Statements: S26; S36/37/39 HS Code: 2933399090 RIDADR: UN 3261…
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Vonoprazan Impurity

Vonoprazan Impurity

  • CAS Number: 1240948-72-4
  • Quantity: 1
  • Purity: 98% min
Chemical Name: 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile
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TAK-438 intermediate 3

TAK-438 intermediate 3

  • CAS Number: 881674-56-2
  • Quantity: 1
  • Purity: 98% min
Synonyms: 1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)- 5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde 5-(2-Fluorophenyl)-1H-pyrrole-3-carboxaldehyde 1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde TAK-438( Vonoprazan fumarate) intermediate 3 5-(2-Fluorophenyl)pyrrole-3-carboxaldehyde
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3-Pyridinesulfonyl chloride HCl

3-Pyridinesulfonyl chloride HCl

  • CAS Number: 42899-76-3
  • Quantity: 1
  • Purity: 98% min
Synonyms: pyridine-3-sulfonyl chloride,hydrochloride; Pyridine-3-sulfonyl chloride hydrochloride; Pyridine-3-Sulfonyl Chloride; Properties: Boiling Point: 314.4ºC at 760 mmHg Melting Point: 120-126ºC Storage Condition: Store below -20ºC
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methyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate

methyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate

  • CAS Number: 1240949-59-0
  • Quantity: 1
  • Purity: 98% min
Synonyms: 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylic acid methyl ester; methyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate